Led by Dr. Anna Halama, Assistant Professor of Research in Physiology & Biophysics, the WCM-Q team combined the already established laboratory technique of implanting cancerous cells into chicken embryos (called in ovo research) with a powerful biochemical analysis method called metabolomics. These two innovative research techniques are combined in a new testing platform that not only gives deeper insights into the ways in which certain types of cancers resist chemotherapy drugs and proliferate, but also delivers significant cost and time savings over existing research methods. The research is considered such a significant breakthrough that it was featured on the front cover of Metabolites, one of the industry’s leading scientific journals. The in ovo technique also has the advantage of costing less and being faster than using mice, while at the same time being much more reliable than simpler cell culture techniques.
Metabolic Signatures of Tumor Responses to Doxorubicin Elucidated by Metabolic Profiling in Ovo
Metabolites 2020, 10, 268
(With the courtesy of Weill Cornell Medicine Qatar)