INOVOTION has collaborated with multiples research teams, and the publications cited provide information about INOVOTION's technology. However if you have any questions or comment, feel free to contact us, our scientific team will be delighted to help you.

 

Brun S, Bassissi F, Serdjebi C, Novello M, Tracz J, Autelitano F, Guillemot M, Fabre P, Courcambeck J, Ansaldi C, Raymond E, Halfon P.
GNS561, a new lysosomotropic small molecule, for the treatment of intrahepatic cholangiocarcinoma.
Invest New Drugs (2019 Feb 19) pp 1-11

Pubmed

 

Arafat K, Al Kubaisy E, Sulaiman S, Karam S, M, Al Natour Z, Hassan A, H, Attoub S.

SMARCAD1 in Breast Cancer Progression.

Cell Physiol Biochem 2018;50:489-500

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P. Gilson, M. Couvet, L. Vanwonterghem, M. Henry, J. Vollaire, V. Baulin, M. Werner, A. Orlowska, V. Josserand, F. Mahuteau-Betzer, L. Lafanechère, J-L. Coll, B. Busser, A. Hurbin.

The pyrrolopyrimidine colchicine-binding site agent PP-13 reduces the metastatic dissemination of invasive cancer cells in vitro and in vivo.

Biochemical Pharmacology (2018)

Pubmed

 

Gilson P, Josa-Prado F, Beauvineau C, Naud-Martin D, Vanwonterghem L, Mahuteau-Betzer F, Moreno A5, Falson P, Lafanechère L, Frachet V, Coll JL, Fernando Díaz J, Hurbin A, and Busser B.
Identification of pyrrolopyrimidine derivative PP-13 as a novel microtubule-destabilizing agent with promising anticancer properties.
Sci Rep. 2017 Aug 31; 7:10209

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E. Al Kubaisy, K. Arafat, O. De Wever, A. H. Hassan, S. Attoub

SMARCAD1 knockdown uncovers its role in breast cancer cell migration, invasion, and metastasis.

Expert Opinion on Therapeutic Targets (2016), 20:9, 1035-1043

Pubmed

 

El Hasasna H, Saleh A, Samri HA, Athamneh K, Attoub S, Arafat K, Benhalilou N, Alyan S, Viallet J, Dhaheri YA, Eid A, Iratni R.
Rhus coriaria suppresses angiogenesis, metastasis and tumor growth of breast cancer through inhibition of STAT3, NFκB and nitric oxide pathways.
Sci Rep. 2016 Feb 18;6:21144.

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Kroiss A, Vincent S, Decaussin-Petrucci M, Meugnier E, Viallet J, Ruffion A, Chalmel F, Samarut J, Allioli N.
Androgen-regulated microRNA-135a decreases prostate cancer cell migration and invasion through downregulating ROCK1 and ROCK2.
Oncogene. 2015 May 28;34(22):2846-55.

Pubmed

 

Mikaelian I, Malek M, Gadet R, Viallet J, Garcia A, Girard-Gagnepain A, Hesling C, Gillet G, Gonzalo P, Rimokh R, Billaud M.

Genetic and pharmacologic inhibition of mTORC1 promotes EMT by a TGF-β-independent mechanism.

Cancer Res. 2013 Nov 15;73(22):6621-31.

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Al Dhaheri Y, Attoub S, Arafat K, Abuqamar S, Viallet J, Saleh A, Al Agha H, Eid A, Iratni R.

Anti-metastatic and anti-tumor growth effects of Origanum majorana on highly metastatic human breast cancer cells: inhibition of NFκB signaling and reduction of nitric oxide production.

PLoS One. 2013 Jul 10;8(7):e68808.

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Prudent R, Vassal-Stermann É, Nguyen CH, Mollaret M, Viallet J, Desroches-Castan A, Martinez A, Barette C, Pillet C, Valdameri G, Soleilhac E, Di Pietro A, Feige JJ, Billaud M, Florent JC, Lafanechère L.

Azaindole derivatives are inhibitors of microtubule dynamics, with anticancer and anti-angiogenic activities.

Br J Pharmacol. 2013 Feb;168(3):673-85.

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