INOVOTION has collaborated with multiples research teams, and the publications cited provide information about INOVOTION's technology. However if you have any questions or comment, feel free to contact us, our scientific team will be delighted to help you.

 

PUBLICATIONS

 

  • Fiorillo M, Scatena C, Naccarato AG, Sotgia F, Lisanti MP.
    Bedaquiline, an FDA-approved drug, inhibits mitochondrial ATP production and metastasis in vivo, by targeting the gamma subunit (ATP5F1C) of the ATP synthase.
    Cell Death Differ. 2021 May 13.
    Pubmed

 

  • Marcion G, Hermetet F, Neiers F, Uyanik B, Dondaine L, Dias AMM, Da Costa L, Moreau M, Bellaye PS, Collin B, Gobbo J, Briand L, Seigneuric R, Kitten O, Cinier M, Garrido C.
    Nanofitins targeting heat shock protein 110: An innovative immunotherapeutic modality in cancer.
    Int J Cancer. 2021 Jun 15; 148(12):3019-3031
    Pubmed

 

  • Byrgazov K, Anderson C, Salzer B, Bozsaky E, Larsson R, Gullbo J, Lehner M, Lehmann F, Slipicevic A, Kager L, Fryknäs M, Taschner-Mandl S.
    Targeting aggressive osteosarcoma with a peptidase-enhanced cytotoxic melphalan flufenamide.
    Ther Adv Med Oncol. 2020 Jul 29.
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  • Leclair HM, Tardif N, Paris A, Galibert MD, Corre S.
    Role of Flavonoids in the Prevention of AhR-Dependent Resistance During Treatment with BRAF Inhibitors.
    Int J Mol Sci. 2020 Jul 16;21(14):5025
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  • Ózsvári B, Magalhães LG, Latimer J, Kangasmetsa J, Sotgia F, Lisanti MP.
    A Myristoyl Amide Derivative of Doxycycline Potently Targets Cancer Stem Cells (CSCs) and Prevents Spontaneous Metastasis, Without Retaining Antibiotic Activity.
    Front Oncol. 2020 Sep 15;10:1528.
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  • Iman W. Achkar,Sara Kader, Shaima S. Dib, Kulsoom Junejo, Salha Bujassoum Al-Bader, Shahina Haya, Aditya M. Bhagwat, Xavier Rousset, Yan Wan, Jean Viallet, Karsten Suhre and Anna Halama
    Metabolic Signatures of Tumor Responses to Doxorubicin Elucidated by Metabolic Profiling in Ovo
    Metabolites 2020, 10(7), 268
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  • Laurie Signetti, Nelli Elizarov, Méliné Simsir, Agnès Paquet, Dominique Douguet, Fabien Labbal, Delphine Debayle, Audrey Di Giorgio, Valérie Biou, Christophe Girard, Maria Duca, Lionel Bretillon, Corine Bertolotto, Bernard Verrier, Stéphane Azoulay and Isabelle Mus-Veteau
    Inhibition of Patched Drug Efflux Increases Vemurafenib Effectiveness against Resistant BrafV600E Melanoma
    Cancers 2020, 12(6), 1500
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  • Brun S, Bassissi F, Serdjebi C, Novello M, Tracz J, Autelitano F, Guillemot M, Fabre P, Courcambeck J, Ansaldi C, Raymond E, Halfon P.
    GNS561, a new lysosomotropic small molecule, for the treatment of intrahepatic cholangiocarcinoma.
    Invest New Drugs (2019 Feb 19) pp 1-11
    Pubmed

 

  • Nascimento BFO, Laranjo M, Pereira NAM, Dias-Ferreira J, Piñeiro M, Botelho MF, Pinho E Melo TMVD.
    Ring-Fused Diphenylchlorins as Potent Photosensitizers for Photodynamic Therapy Applications: In Vitro Tumor Cell Biology and in Vivo Chick Embryo Chorioallantoic Membrane Studies.
    ACS Omega. 2019 Oct 9;4(17):17244-17250.
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  • Alsamri H, El Hasasna H, Al Dhaheri Y, Eid AH, Attoub S, Iratni R.
    Carnosol, a Natural Polyphenol, Inhibits Migration, Metastasis, and Tumor Growth of Breast Cancer via a ROS-Dependent Proteasome Degradation of STAT3.
    Front Oncol. 2019 Aug 8;9:743
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  • Arafat K, Al Kubaisy E, Sulaiman S, Karam S, M, Al Natour Z, Hassan A, H, Attoub S.
    SMARCAD1 in Breast Cancer Progression.
    Cell Physiol Biochem 2018;50:489-500
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  • P. Gilson, M. Couvet, L. Vanwonterghem, M. Henry, J. Vollaire, V. Baulin, M. Werner, A. Orlowska, V. Josserand, F. Mahuteau-Betzer, L. Lafanechère, J-L. Coll, B. Busser, A. Hurbin.
    The pyrrolopyrimidine colchicine-binding site agent PP-13 reduces the metastatic dissemination of invasive cancer cells in vitro and in vivo.
    Biochemical Pharmacology (2018)
    Pubmed

 

  • Gilson P, Josa-Prado F, Beauvineau C, Naud-Martin D, Vanwonterghem L, Mahuteau-Betzer F, Moreno A5, Falson P, Lafanechère L, Frachet V, Coll JL, Fernando Díaz J, Hurbin A, and Busser B.
    Identification of pyrrolopyrimidine derivative PP-13 as a novel microtubule-destabilizing agent with promising anticancer properties.
    Sci Rep. 2017 Aug 31; 7:10209
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  • E. Al Kubaisy, K. Arafat, O. De Wever, A. H. Hassan, S. Attoub
    SMARCAD1 knockdown uncovers its role in breast cancer cell migration, invasion, and metastasis.
    Expert Opinion on Therapeutic Targets (2016), 20:9, 1035-1043
    Pubmed

 

  • El Hasasna H, Saleh A, Samri HA, Athamneh K, Attoub S, Arafat K, Benhalilou N, Alyan S, Viallet J, Dhaheri YA, Eid A, Iratni R.
    Rhus coriaria suppresses angiogenesis, metastasis and tumor growth of breast cancer through inhibition of STAT3, NFκB and nitric oxide pathways.
    Sci Rep. 2016 Feb 18;6:21144.
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  • Kroiss A, Vincent S, Decaussin-Petrucci M, Meugnier E, Viallet J, Ruffion A, Chalmel F, Samarut J, Allioli N.
    Androgen-regulated microRNA-135a decreases prostate cancer cell migration and invasion through downregulating ROCK1 and ROCK2.
    Oncogene. 2015 May 28;34(22):2846-55.
    Pubmed

 

  • Mikaelian I, Malek M, Gadet R, Viallet J, Garcia A, Girard-Gagnepain A, Hesling C, Gillet G, Gonzalo P, Rimokh R, Billaud M.
    Genetic and pharmacologic inhibition of mTORC1 promotes EMT by a TGF-β-independent mechanism.
    Cancer Res. 2013 Nov 15;73(22):6621-31.
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  • Al Dhaheri Y, Attoub S, Arafat K, Abuqamar S, Viallet J, Saleh A, Al Agha H, Eid A, Iratni R.
    Anti-metastatic and anti-tumor growth effects of Origanum majorana on highly metastatic human breast cancer cells: inhibition of NFκB signaling and reduction of nitric oxide production.
    PLoS One. 2013 Jul 10;8(7):e68808.
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  • Prudent R, Vassal-Stermann É, Nguyen CH, Mollaret M, Viallet J, Desroches-Castan A, Martinez A, Barette C, Pillet C, Valdameri G, Soleilhac E, Di Pietro A, Feige JJ, Billaud M, Florent JC, Lafanechère L.
    Azaindole derivatives are inhibitors of microtubule dynamics, with anticancer and anti-angiogenic activities.
    Br J Pharmacol. 2013 Feb;168(3):673-85.
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PATENTS

 

  • Kotora et al.
    15p-substituted estrone derivatives as selective inhibitors of 17p-hydroxysteoid-dehydrogenases, method of preparation and use thereof.
    WO2017/211330. December 14, 2017

 

  • Guedat and Miniou.
    Method of treating cancer with a combination of benzylideneguanidine derivatives and chemotherapeutic agent.
    WO2017/021216 A1. February 9, 2017

 

  • Lafanechère et al.
    5-Azaindole compounds with anticancer and antiangiogenic activities.
    WO2014/033597 A1. March 6, 2014.